Enzyme Solutions for Dietary Supplements

Let Us Help You Customize an Enzyme Solution to Support Digestive Health

The human digestive system facilitates a dynamic and sophisticated response to food. Critical to digestion are enzymes. Our bodies produce enzymes in the salivary glands, stomach, pancreas, and small intestine. Supplemental microbe- and plant-based, acid-resistant enzyme formulations are designed to complement our own biology.

Protease
Enzymes to help digest proteins into amino acid building blocks

Lipase
Enzymes to help break down fats into energy-rich fatty acids

Amylase
Enzymes to help digest starch carbohydrates

Lactase
Enzyme to digest lactose

Carbohydrases
To help break down hard-to-digest carbohydrates and plant fibers

Phytase
To help release nutrients and minerals from plants

Custom Enzyme Solutions

Close up of pills

From concept to reality, we will guide you through every step to ensure intelligent design, optimized performance, and differentiated enzyme product offerings.

Learn More

Lipase

Coconut and avocado sliced open

Lipases are required to digest fats and triglycerides into free fatty acids. We regularly recommend microbial lipase for broad spectrum multi-enzyme formulations. Talk to the BIO-CAT team about our internal studies of lipase activity and how much lipase to include in your next product formulation.

Learn More

Protease

Chopsticks picking up cooked beef out of a bowl of soup

Proteases are required to digest proteins into amino acid building blocks. Our portfolio of microbial and plant proteases features enzymes with both endopeptidase and exopeptidase activities that work across a broad range of pH values. Ask the BIO-CAT team about specific proteases that are best suited for your product formulation.

Learn More

Amylase and Other Carbohydrases

Potatoes and rice, uncooked

Amylases help digest long chains of glucose called starch—the most common carbohydrate in the human diet. Humans naturally produce alpha-amylase in saliva and pancreatic “juice” to trim down starch into shorter chain oligosaccharides and disaccharides. Additional starch carbohydrases in the BIO-CAT portfolio include glucoamylase, invertase, maltase, and diastase.

Learn More

Lactase

various aged cheeses

Also known as beta-galactosidase, lactase converts the disaccharide milk sugar called lactose into the monosaccharides glucose and galactose. In individuals with lactose intolerance, oral supplementation with microbial lactase has been shown to help reduce symptoms of gastrointestinal distress such as bloating and flatulence. Increasingly, lactase is added to multi-enzyme formulations to support digestion.

Learn More

Other Non-Starch Carbohydrases

Fresh uncooked corn on the cob

Similar to cellulase and alpha-galactosidase, a number of additional carbohydrase enzymes are approved for use in dietary supplements. These enzymes are commonly included in formulations targeting improved digestion of the complex carbohydrates and fibers commonly found in vegetables and plant-based foods. Examples include hemicellulase, xylanase, beta-glucanase, and pectinase.

Learn More

Alpha-Galactosidase

black beans in a wooden spoon

The alpha-galactosidase enzyme cleaves off terminal galactose residues from galactosylated molecules, one of which is galactooligosaccharide (GOS). GOS is a complex carbohydrate found in beans, dairy products, and certain root vegetables. In individuals with certain food intolerances, oral supplementation with microbial alpha-galactosidase has been shown to help reduce symptoms of gastrointestinal distress such as bloating and flatulence. Increasingly, alpha-galactosidase is added to multi-enzyme formulations to support digestion.

Learn More

Transglucosidase

various breads

Transglucosidase belongs to the alpha-glucosidase family of enzymes that can hydrolyze the disaccharide maltose into glucose. In addition, transglucosidase facilitates the elongation of maltose to longer malto-oligosaccharides such as the trisaccharides panose and isopanose that are partially resistant to digestion by human pancreatic enzymes. Rather, several species of human gut microbes such as Lactobacillus and Bifidobacterium have been shown to effectively metabolize malto-oligosaccharides.

Learn More

Phytase

Fresh uncooked corn on the cob

Phytase is an enzyme that helps release certain minerals such as zinc from a common plant molecule called phytic acid or phytate. Phytate is commonly found in beans, seeds, nuts, and grains.

Learn More

Cellulase

Cellulase is an enzyme that breaks down cellulose, which is a type of non-starch polysaccharide (NSP). Cellulose is the main structural component of plant cell walls and vegetable fiber. Human cells do not make or secrete their own cellulase. Our guts rely heavily on bacteria to break down plant fiber in a process called microbial fermentation, which can lead to gas and bloating.

Learn More

OPTI-ZIOME P3 HYDROLYZER™

A woman running with an inset image of pea pods

Proprietary triple protease blend with broad substrate specificity that is ideal for the digestion of plant, animal, and dairy proteins*,**

In vitro gastric simulation showed:
· 70% better branched chain amino acid release from whey protein*,**
· 295% better leucine release from plant protein (average of pea and soy protein)*,**
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
**Derived from standard in vitro gastric simulation experiments that showed increased amino acid liberation by OPTI-ZIOME P3 HYDROLYZER™ compared to two top competitors.

Learn More

OPTI-ZIOME™ GluteAx

various breads

Blend of proteases specifically formulated to facilitate the breakdown of gluten and associated peptides*,†,‡

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
†This product is not intended to replace a gluten-free diet or treat or prevent celiac disease.
‡Derived from standard in vitro gastric simulation experiments that showed decreased alpha-gliadin abundance following wheat gluten slurry hydrolysis.

Learn More

Fungal Pepsin

measuring cup filled with powder

Fungal Pepsin is an alternative to animal derived pepsin. Fungal Pepsin acts just like animal derived pepsin hydrolyzing proteins but without the animal derivatives commonly found in traditional pepsin.

Learn More

Microbial Trypsin

Microbial Trypsin is a non animal derived Trypsin alternative. It is comparable to traditional trypsin in pH profile activity and performance.

Learn More

Microbial Pancreatin

Microbial Pancreatin, is non-animal-derived and comparable in activity and performance to traditional pancreatin. Microbial Pancreatin digest protein fat and starch and is available in strengths 1x to 10x.

Learn More

Learn About Our Services

Custom Formulation

The right enzyme or microbial for your precise application

Custom Blending

Large blending capacity, production and packaging

Custom Product Development

Your partner in innovating new products

Custom R&D Projects

From basic research through development and tech support

Quality Assurance & Control Support

Every product rigidly tested in our in-house lab

Regulatory Support

Regulation review, safety, import/export and more

Let’s Develop Something Together

We’re as passionate as you are about scientific innovation that matters

Learn More