Although the effects of microorganisms on the human body have been discussed and studied for well over a century, research specifically on microbes of the human gut has intensified over the past decade. This research has led to the discovery of commensal and beneficial bacterial species that support healthy physiology in the human gut. In addition, oral supplementation with live microbes, or probiotics, has become increasingly popular.
Probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. This globally recognized definition sets a critical requirement that probiotics, such as certain strains of Lactobacillus, Bifidobacterium, and Bacillus, demonstrate a health benefit in a properly designed clinical study. Examples of substantiated health benefits of probiotics include the support of gastrointestinal health, immune health, and promotion of the growth of beneficial gut bacteria. However, Bacillus species in particular exhibit several attributes well suited for use in dietary supplements and food.
Bacillus subtilis MB40 (hereafter referred to as “MB40”), the patented gram-positive strain in BIO-CAT Microbials’ OPTI-BIOME® Bacillus subtilis MB40, is uniquely positioned to excel as a probiotic. MB40 is a soil-borne, safe, non-GMO strain that naturally creates a very thick and durable coating when it transitions to a spore form. As a spore, MB40 is durable in harsh environments and survives long term storage. Additionally, MB40 is metabolically diverse and able to produce a wide variety of beneficial bioactive compounds such as vitamins and digestive enzymes.